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Scientific publications

Publications & Resources

  1. Nikolaivits, E.; Siaperas, R.; Agrafiotis, A.; Ouazzani, J.; Magoulas, A.; Gioti, A.; Topakas, E. Functional and transcriptomic investigation of laccase activity in the presence of PCB29 identifies txo novel enzymes and the multicopper oxidase repertoire of a marine-derived fungus. Science of The Total Environment. 2021, 775, 145818.
  2. Sripan, D.; Wilantho, A.; Khitmoh, K.; Wongsawaeng, D.; Ouazzani, J.; Chavanich, S.; Tongsima, S.; Somboona, N.; Marine Bacteria Community in 150m Depth Tachai Island, the Southeast Andaman Sea of Thailand. Front. Mar. Sci. 2021, 8, 624624.
  3. Letsiou, S.; Bakea, A.; Le Goff, G.; Lopes, P.; Gardikis, K.; Weis, M.; Benayahu, Y.; Ouazzani, J. Marine fungus Aspergillus chevalieri TM2-S6 extract protects skin fibroblasts from oxidative stress. Mar. Drugs. 2020, 18(9), 460.
  4. Said Hassane, C.; Fouillaud, M.; Le Goff, G.; Sklirou, A. D.; Boyer, J. B.; Trougakos, I. P.; Jerabek, M.; Bignon, J.; De Voogd, N. J.; Ouazzani, J.; Gauvin-Bialecki, A.; Dufossé, L. Microorganisms associated with the marine sponge Scopalina hapalia: A reservoir of bioactive molecules to slow down the aging process. Microorganisms. 2020, 8, 1262.
  5. Campos, P.-E.; Herbette, G.; Chendo, C.; Clerc, P.; Tintillier, F.; De Woogd, N. J.; Papaganou, E. D.; Trougakos, I. P.; Jerabek, M.; Bignon, J.; Le Goff, G.; Ouazzani, J.; Gauvin-Bialecki, A. Osirisynes G-I, new long-chain hightly oxygenated polyacetylenes from Mayotte marine sponge Haliclona sp. Mar. Drugs. 2020, 18(7), 350.
  6. Letsiou, S.; Bakea, A.; Le Goff, G.; Lopes, P.; Gardikis, K.; Alonso, C.; Alvarez, P.A. and Ouazzani, J. In vitro protective effects of marine-derived Aspergillus puulaauensis TM124-S4 extract on H2-O2-stressed primary human fibroblasts. Toxicology in Vitro. 2020, 66, 104869
  7. Nikolaivits, E.; Agrafiotis, A.; Baira, E.; Le Goff, G.; Tsafantakis, N.; Chavanich, S.; Benayahu, Y.; Ouazzani, J.; Fokialakis, N. and Topakas, E. degradation mechanism of 2,4-dichlorophenol by fungi isolated from marine invertebrates. Int. J. Mol. Sci. 2020, 21, 3317
  8. Gioti, A.; Siaperas, R.; Nikolaivits, E.; Le Goff, G.; Ouazzani, J.; Kotoulas, G. and Topakas, E. Draft genome sequence of a Cladosporium species isolated from the mesophotic ascidian Didemnum maculosum. Micriobiol. Resour. Announc. 2020, 9, 18, e00311-20
  9. Imahara, Y.; Chavanich, S.; Viyakarn, V.; Kushida, Y.; Reimer, J.D. and Fujita, T. Two new species of the genus Chironephthya (Octocorallia, Alcyonacea, Nidaliidae, Siphonogorgiinae) from the Gulf of Thailand. Zootaxa. 2019, 4780, 2
  10. Tsakiri, E.N., Gumeni, S., Iliaki, K.K., Benaki, D., Vougas, K., Sykiotis, G.P., Gorgoulis, V.G., Mikros, E., Scorrano, L. and Trougakos, I.P. Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation. Ageing Cell. 2019, 18(1):e12845
  11.  Campos, P.E.; Pichon, E.; Moriou, C.; Clerc, P.; Trépos, R.; Frederich, M.; De Voogd, N.; Hellio, C.; Gauvin-Bialecki, A. and Al-Mourabit, A. New antimalarial and antimicrobial tryptamine dérivatives from marine sponge Fascaplysinopsis reticula. Mar. Drugs. 2019, 17, 167
  12. Evangelekou, Z.; Manola, M.; Gumeni, S. and Trougakos, I.P. Nutrigenomics as a tool to study the impact of diet on ageaing and age-related diseases: the Drosophila approach. Gene and Nutrition. 2019, 14, 12
  13. Le Goff, G.; Lopes, P.; Arcile, G.;Vlachou, P.; Van Elslande, E.; Retailleau, P.; Gallard, J.-F.; Weis, M.; Benayahu, Y.; Fokialakis, N. and Ouazzani, J. Impact of cultivation technique on the production of secondary métabolites by Chrysosporium lobatum TM237-S5, isolated from the sponge Acanthella cavernosa. Mar. Drugs. 2019, 17, 678
  14. Nikolaivitis, E.; Agrafiotis, A.; Termentzi, A.; Machera, K.; Le Goff, G.; Alvarez, P.; Chavanich, S.; Benayahu, Y.; Ouazzani, J.; Fokialakis, N. and Topakas, E. Unraveling the detoxification mechanism of 2,4-dichlorophenol by marine-derived mesophotic symbiotic fungi isolated from marine invertebrates. Mar. Drugs. 2019, 17, 564
  15. Reimer, J.D.; Kise, H.; Santos, M.E.A.; Lindsay, D.J.; Pyle, R.L.; Copus, J.M.; Bowen, B.W.; Nonaka, M.; Higashiji, T. and Benayahu, Y. Exploring the biodiversity of understudied benthic taxa at mesophotic and deeper depths: examples from the order Zoantharia (Anthozoa:Hexacorallia). Front. Mar. Sci. 2019, 6, 305
  16. Benayahu, Y. et al. (2019) Octocorals of the Indo-Pacific. In: Loya, Y.; Puglisse, K.; Bridge, T.; (eds) Mesophotic Coral Ecosystems. Coral Reefs of the World, vol 12. Springer, Cham
  17. Sklirou, A.; Papanagnou, E.D.; Fokialakis, N.; and Trougakos, I.P. Cancer chemoprevention via activation of proteostatic modules. Cancer Letters. 2018, 413, 110
  18. Nikolaivits, E.; Dimarogona, M.; Karagiannaki, I.; Chalima, A.; Fishman, A. and Topakas, E. Versatile fungal polyphenol oxidase with chlorophenol bioremediation potential: characterization and protein engineering. Appl. Environ. Microbiol. 2018, 84:e01628-18
  19. Liberman, R., Shlesinger, T., Loya, Y. and Benayahu Y. Octocoral sexual reproduction: temporal disparity between mesophotic and shallow-reef populations. Front. Mar. Sci. 2018, 5, 445
  20. Bulan, D.E., Wilantho, A., Krainara, P., Viyakarn, V., Chavanich, S. and Somboonna, N. Spatial and seasonal variability of reef bacterial communities in the upper Gulf of Thailand. Front. Mar. Sci. 2018, 5, 441
  21. Bulan, D.E., Wilantho, A., Tongsima, S., Viyakarn, V., Chavanich, S. and Somboonna, N. Microbial and small eukaryotes associated with reefs in the upper Gulf of Thailand. Front. Mar. Sci. 2018, 5, 436
  22. El-Demerdash, A.; Moriou, C.; Toullec, J.; Besson, M.; Soulet, S.; Schmitt, N.; Petek, S.; Lecchini, D.; Debitus, C. and Al-Mourabit, A. Bioactive Bromotyrosine-Derived Alkaloids from the Polynesian Sponge Suberea ianthelliformis. Mar. Drugs. 2018, 16(5), 146
  23. Vlachou, P.; Le Goff, G.; Alonso, C.; Álvarez, P.A.; Gallard, J.-F.; Fokialakis, N. and Ouazzani, J. Innovative Approach to Sustainable Marine Invertebrate Chemistry and a Scale-Up Technology for Open Marine Ecosystems. Mar. Drugs. 2018, 16(5), 152
  24. Papanagnou, E.D.; Terpos, E.; Kastritis E.; Papassideri, I.S.; Tsitsilonis O.E.; Dimopoulos, M.A. and Trougakos, I.P. Molecular responses to therapeutic proteasome inhibitors in pultiple myeloma patients are donor-, cell type- and drug-dépendent. Oncotarget. 2018, 9(25), 17797
  25. Van Soest, R.W.M. and De Voodg, N.J. Calcareous sponges of the Western Indian Ocean and Red Sea. Zootaxa. 2018, 4426(1), 1–160
  26. Nikolaivits, E.; Dimarogona, M.; Fokialakis, N. and Topakas, E. Marine-Derived Biocatalysts: Importance, Accessing, and Application in Aromatic Pollutant Bioremediation. Front. Microbiol. 2017, 8, 265
  27. Benayahu. Y., McFadden, C.S., Shoham, E. and Van Ofwegen, L.P. Search for mesophotic octocorals (Cnidaria, Anthozoa) and their phylogeny. II. A new zooxanthellate species from Eilat, northern Red Sea. ZooKeys. 2017, 676, 1
  28. Sklirou, A.D.; Gaboriaud-Kolar, N.; Papassideri, I.; Skaltsounis, A.L. and Trougakos, I.P. 6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts. Sci. Rep. 2017, 7, 11713
  29. Benayahu, Y.; McFadden, C.S. and Shoham, E. Search for mesophotic octocorals (Cnidaria, Anthozoa) and their phylogeny: I. A new sclerite-free genus from Eilat, northern Red Sea. ZooKeys. 2017, 680, 1
  30. Tsakiri, E.N.; Terpos, E.; Papanagnou, E.D.; Kastritis, E.; Brieudes, V.; Halabalaki, M.; Bagratuni, T.; Florea, B.I.; Overkleeft, H.S.; Scorrano, L.; Skaltsounis, A.L.; Dimopoulos, M.A. and Trougakos I.P. Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events. Sci. Rep. 2017, 7, 17802
  31. Leman-Loubière, C.; Le Goff, G.; Debitus, C. and Ouazzani, J. Sporochartines A-E, a new family of natural products from the marine fungus Hypoxylon monticulosum isolated from Sphaerocladina sponge. Front. Mar. Sci. 2017, 4, 399
  32. Leman-Loubière, C.; Le Goff, G.; Retailleau, P.; Debitus, C. and Ouazzani, J. Sporothriolide-Related Compounds from the Fungus Hypoxylon monticulosum CLL-205 Isolated from a Sphaerocladina Sponge from the Tahiti Coast. J. Nat. Prod. 2017, 80, 10, 2850
  33. Gumeni, S.; Evangelakou, Z.; Gorgoulis, V.G. and Trougakos, I.P. Proteome Stability as a Key Factor of Genome Integrity. Int. J. Mol. Sci. 2017, 18, 10, 2036
  34. Tsakiri, E.N.; Gaboriaud-Kolar,N.; Iliaki K., Tchoumtchoua,J.; Papanagnou, E.D.; Chatzigeorgiou, S.; Tallas, K.D; Mikros, E.; Halabalaki, M.; Skaltsounis, A.L. and Trougakos I.P. The Indirubin Derivative 6-Bromoindirubin-3′-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects. Antioxidants & Redox Signaling, 2017, 27, 14, 1027
  35. Gumeni, S. and Trougakos, I.P. Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease Oxidative Medicine and Cellular Longevity. Oxidative Medicine and Cellular Longevity, 2016, ID 4587691